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Page HERALD Wednesday April 17 lll Cancer research ongoing the early days cancer researchers were faced with the complex puzzle of trying to figure out what cancer is and what causes it And while there have been many significant milestones in cancer research along the road it has only been within the last 15 years that tremendous ad vances have been made towards understanding the cancer pro cess of the mechanism that causes a normal cell to become a cancer cell growing wildly out of control One of the newest focuses in cancer research that has shed light on the cancer puzzle is the field of oncogenes And one of the foremost cancer researchers dying oncogenes in Canada Dr Tony says research in this area will eventually result in a greatly improved ability to diagnose and cure cancers s research is funded by the National Cancer Institute of Canada the research filiate of the Canadian Cancer which will spend 32 million on cancer research pro jects in Canada this Since 1981 Pawson has awarded more than l million in NCIC grants to oncogenes and he is a Terry Fox Cancer Research Scientist at For more than a decade Pawson and other researchers have known that oncogenes or more proto oncogenes are found in cell of the human body According to Pawson a senior scientist at the Molecular and Developmental Biology Division at Toronto s Mount Sinai Hospital and a noted international autnorl on oncogene research People find it difficult to understand why we have these genes in the first place Bui obviously if we have them they must be doing something important and that turns out to be the case When in their normal state oncogenes are the blueprints for the proteins that regulate the way cells naturally grow and divide Most of the time proto oncogenes don cause any pro But if they become mutated for some reason by radiation the carcinogens in cigarette smoke even certain ruses can become active oncogenes Mutated oncogenes cause the cell to replicate faster and faster without stopping This process is the very definition of cancer uncontrolled growth of cells But oncogenes of which about ion have been are part of tht story Coun er balancing the action of these cell growth promoters are the more recently discovered tumour supressor genes or anti oncogenes about which less is known While oncogenes product proteins that encourage cell growth anti oncogenes carry the codefor growth slowing protein When an oncogene stops working for some reason or if it is missing from a cell the cell won any growth protein Consequent cell growth will become more rapid cancer style uses the analogy of an automobile to demonstrate how these two types of genes work likening to the brakes He says Cancer cells are like a car with Us accelerator stuck and its brake line cut It keeps going faster and faster with nothing Although any cell could poten become cancerous Pawson points out that humans are fairly well guarded against such a development Otherwise none of us would live lo old age without developing tumours Normal cells don t turn into cancer cells overnight as the result of mutations in a single gene explains It re quires a succession of mutations of different protooncogenes and tumour suppressor genes before a malignant tumour can begin to develop Complex as these mechanisms may be cancer researchers such as Pawson are studying the way oncogenes and the proteins they produce behave so that their ac tion can be blocked Last year and his NCIC team made an exciting discovery in this area when they identified a common element in many oncogene produced pro teins Says Pawson We looked for similarities in the proteins produced by oncogenes and discovered there was a large of proteins that basically in the same way Many human tumours have produced proteins belonging to this class says that years of cancer research has revealed that what once seemed trabh complex now seems to have an underlying theme or simplicity about it And thats tremendously exciting You can help ensure that such promising cancer research con by contributing generously to the Canadian Cancer Society protests demolition The demolition of the house on 337 Maple Avenue by its Owner Burl based developer Frank Zupet Saturday is legal but it not right said Gail Rutherford President of the local group Residents Ac in Development Decisions in a press release Mr Zupet has an application before the Town s planning staff to use the property at 333 and 337 Maple Avenue for two condominiums According to Ms Rutherford Mr is tearing a neighborhood on speculation because the development application has yet to go before Hills Council for consideration will be holding public meeting April 24 at Park Public School in Georgetown starting at on the Maple Avenue proposal GEORGETOWN DISTRICT CHRISTIAN SCHOOL WHY CHRISTIAN EDUCATION Is there anything more important than that your child receive an education that is consistent with your basic beliefs and principles VISIT OUR OPEN HOUSE WEDNESDAY APRIL 24th 130300 700830 LOCATED ON TRAFALGAR ROAD KM NORTH OF MAPLE AVENUE INTERESTED PARENTS CAN CALL 8774221 Resident wins award The Ottawa- and District Boys Work Committee has selected Tom of Georgetown lo receive the James MacGregor Award and Trophy for This award is presented to Canadians who have made con in the area of youth work It will be presented in May at an Ottawa reception People across Canada are nominated and the Boys Work Selection Committee forwards its choice to the Ottawa and District Boys Work Committee which ratifies the Committees mendation Mr was Georgetown s Citizen of the Year and a former president of the Secondary School Teachers Federation He was recently informed of the award Mr said is a great honour and privilege to be selected as the J MacGregor Award winner J was a Cana dian of remarkable qualities who served this country with great distinction in times of war and peace It is indeed a pleasure to join the ranks of the previous recipients and to associate with such a great Canadian Karen and Ryan say Thanks Karen and Ryan of Public School and the other students of the Halton Board of Education want to thank the hundreds of volunteers who help out in schools Their work is appreciated not just during Volunteer Week but throughout the year If you would like to help out contact your local school If you are a senior and would like to be part of the Grand Time Seniors Volunteer Program please call or 416 8788451 Pursuing Excellence in Education Through Commitment and Service Bill Harrison Bob Williams Director of Education EDUCATION LETS TALK OF ALL THE DRIVING SCHOOLS YOU CAN CHOOSE ONLY ONE HAS STUDENTS TO RECOMMEND IT At Young Drivers of Canada we offer one of the most thorough defensive driver training programs in the country We believe the best way to learn is with one instructor and one student in the car on 11 learn how lo drive defen sively with our piovcn to accident frredifving alsnieceiu exclusive in class instruction highlytrained to make sure you understand all the the defensive driving techniques I earn emergency maneuvers like brake andavoiud threshold braking swerving techniques and how to avoid a head on or rearend collision Dont take a chance I eta professional teach you to dine and survive Georgetown Acton And Surrounding Areas YOUNG DRIVERS OF CANADA NEXT COURSE STARTS ON WED MAY 8th 630938 pm Wed Thurs 8770751