Oakville Beaver, 24 Mar 1993, p. 16

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MCCALL’S OUR ENTIRE STOCK! natural gas - tlon't wait another minute.CaU U Gas today, and ask about these and other EnerSmart offers available on selected home comfort heating and cooling equipment. See a Member Dealer for other purchase incentives. Ila/(w [be EnerSmart Choice/ Whether youve replacing or converting to lgas - don't wait another minuteCall Union SALE ENDS MARCH 27TH M M " Oakville Beaver Staff How immune system controls inflammation may cause C rohn's Over 100 people packed the Oakville Room of the municipal building recently to hear a researcher speak on inflammatory bowel disease (IBD). Of these peo- ple, 36 stayed behind to discuss starting a group of their own. Along with anyone else interest- ed, they will meet Monday to for- mulate plans for a chapter, said Linda Noble of the Crohn's and Colitis Foundation of Canada. When formed, Oakville's will be the 91st chapter in Canada and the 3lst in Ontario. Since it began in 1974, the Foundation has grown to 12,500 members in Canada and has raised $13 million to support individual researchers and to establish research units at the University of Calgary and at McMaster University. From the latter unit came Dr. Ken Croitoru, guest speaker.. Over l Oakville I building researcher bowel dise ple, 36 st starting as By BARB JOY Croitoru defined the difference between Crohn's disease and ulcer- ative colitis, two forms of IBD. The latter is confined to the large intes- tine while Crohn's can attack any part of the digestive tract from mouth to anus (or "cheek to cheek", SHOP OAKVILLE on our heating and cooling package, or choose a free Honewell Heclronic Air Cleaner and setback thermostat Plus make no payments/or 90 Days ." Call Union Gas Today! 335-7310 Each dollar spent shopping in Oakville brings financial benefits to our community. Local merchants employ your friends, neighbours and families, and provide much of the tax revenue needed to support your municipal services. QPRO/ECT OF THE OAKVILLE CHAMBER OF COMMERCE as Croitoru put it) but usually affects the small intestine. Their symptoms ---including severe diar- rhea, loss of appetite, weight loss and abdominal cramps - have sometimes been confused with appendicitis. Only after surgery has the true diagnosis been established, said the researcher. " Worth ttl i HIGH INCIDENCE RATE "Usually in four to six weeks, there's an amazing difference," said the researcher. "Whether it's because the kid is getting fed or whether the inflammation in the bowel is healing (because it is rest- ing), we don't know." Why it works may be attributable to the fact that it has no protein and is not allergenic or anti- genic and therefore does not stimu- late the immune system. Diet is also fundamental to a book written by Elaine Gottschall. Food and the Gut Reaction - Intestinal Health Through Diet - advises the avoid- ance of carbohydrates and empha- sizes natural rather than refined sugars. The book is stuffed with recipes deemed beneficial to people with IBD. For more information on Crohn's and Colitis, call the Crohn's and Colitis Foundation of Canada at 1- 800-387-1479. IBD children apparently adjust to their illness better than adults. Croitoru said many children can readily push a tube of pre-digested feeding solution down the backs of their throats and into their stomachs at night and, while they sleep, allow it to become absorbed into their blood stream without entering the intestines. The tubes are removed before they go to school. ing bag. This may be eliminated in the future as more surgeons are leaving the muscles of the anus intact and connecting the small intestine to them, part of which serves as a surrogate pouch, accord- ing to Foundation literature. "Lack of fibre has long been a suspected cause of IBD because African populations that consume high fibre diets tend to have less IBD than westerners." it said. "But this idea has not been confirmed." To counteract symptoms, IBD sufferers take corticosteroid, immunosuppressants, antibacterial and antibiotic drugs. All have adverse side effects which pharma- ceutical companies are trying to eradicate. If medication is not effec- tive, surgery may be necessary. The removal of the entire colon (large intestine) cures ulcerative colitis since, unlike Crohn's, it is the only part affected. However, it leaves the patient with the necessity to dispose of waste with an external stool collect- Recent studies indicated that people with Crohn's disease tended to eat a lot of refined sugar but Foundation material pointed out that these studies did not take into account the possibility that people with Crohn's are often malnour- ished and might consume sugar to get quick energy. This does not mean sugar is the cause. Nor does the consumption of fibrous com- flakes. In the meantime, theories still abound as to the cause of IBD. Environmental factors such as bac- teria and fungus have not been sub- stantiated, said Croituro. Nor has diet and stress. "Although stress might make it worse, there's no evidence that it's the cause," he said. Noting that inflammation is the body's response to such damages as cuts and burns, the question arises as to why constant inflammation is present in the bowel and how it can be controlled. He said researchers are investigating how the "bad" antibodies (the body's fighters) pro- duced in the intestine can be kept in check so that they do not produce the damaging inflammation seen in IBD sufferers. They are looking at T-cells in the thymus which recognize what is foreign to the particular person's physical makeup and needs to be attacked. These are the cells that fight to reject transplanted organs they consider invaders. But how they "see" what is foreign and what isn't is of crucial importance to researchers. Croitoru held out hope that one day a vaccine, "a superanti- gen," might be produced from bac- teria toxins or viruses that would control T-cell behavior. Although researchers have made some head- way in that they have discovered the receptor of T-cells, he said there is a long way to go. Dr. Ken Croitoru DIET AND STRESS TUBE FEEDING

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