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12 -. PORT PERRY STAR - Tuesday, Fébruary 27, 2001 . "Scugog's Community Newspaper of Choice" 0 2 BX F 3 J ] J a \NQplort Aj % a Zi OF BH &1 | | / | | i CAL LEY [6686 Yonge Si. RENTER ITCRA Newmarket Uabridgg ELI ERE YAS RIIR! NW Brock & Man (D905) 852-5010 { - id I nb "Ti Store Hours: Vion-1 nt Lakeridge Health involved in effort Durham heart patients may take part in Harvard study Patients suffering from heart disease may have an opportunity to participate in an international multi- centre study conducted by Harvard Medical School. The research team at Lakeridge Health Oshawa will be led by cardiologist Dr. Rakesh Bhargava and Andrea "McCallum, Research Coordinator. Four thousand patients admitted to hospital with - heart attack or angina may be eligible to participate in-the study. | Recent evidence has suggested that infection specifically with an infec- tious organism Chlamydia Pneumoniae, may play a role in development of cholesterol deposit in sjclujm ajulelals sfais|s Eft |R{A ejajnit|y Afvioln s|vieim Flajrinis clalnja sjefainjeje|s Afr le Hie|Rr oOfRIR gixjcli isle sft jsis}i |E]S olm|eln IAfo tw ia Ld cleje]s sjojriajs sjojaja Kiajuiejr Ajnjojuis pli |c MiAIALS EjnjajmieiL]s clajsii jujo nit jo AlBjcC A{RiT pltjLiajrie]s Blafajs Tiajrle|s njuiola Alc ju A{Ljoln]e eisjajfn tit |o}s siajLie]s pjAaimia understand _the role. of arteries and resulting heart attacks and strokes. All patients volunteer- ing to participate in the study will be treated with cholesterol lowering drugs. Half of the patients will get antibiotics one week a month for 18 months and the other half no antibi- otics. They will be followed closely for heart attacks and strokes for a two-year period. oa Dr. Rakesh Bhargava describes coronary arter- ies with cholesterol plaque as "a smoldering artery." "Infection may be the spark which ignites the fire and rupture of the plaque leading to angina and heart attack," he said. "The aim of treatment will be to reduce fat in the arteries and extinguish any sparks of infection." The Prove-It trial com- pares two cholesterol-low- ering drugs with estab- lished benefits in reducing evidence of recurrent angi- na, heart attacks and death - Pravachol and Lipitor. Additionally, to further infection in cardiovascular disease this study will evaluate the effectiveness of antibiotic Glatiflokacin therapy in reducing cardio- vascular events in combi- nation with cholesterol reducing drugs. Antibiotic Glatiflokacin is approved in the U.S. and several other non- European countries for the treatment - of pneumonia, bronchitis, sinusitis and urinary infections. Emerging evidence sug- gests that inflammation plays an important role in the initiation, progression and complications of hard- ening and cholesterol deposition. in arteries of the heart. ' Evidence is strongest for chlamydia pneumoniae infections. Epidemiological stud- ies report a more than two- fold increase in the risk for heart attack among patients which evidence of C. Pneumoniae exposure. More frequent exposure to chlamydia infections 'appeared to result in more significant disease. In addition, studies sug- gest synergism between infection and high choles- terol levels. The Research Institute at Lakeridge Health and Harvard Medical School Cardiac Research division a have been collaborating in research under the leader- ship of Dr. Rakesh Bhargava for the past decade, bringing advances in treatment of cardiac dis- eases at no cost to patients and savings for the health care system. Grandview offers March Break program for kids A fun-filled week of activities are available during March Break for kids with special needs living in Durham Region. . On Monday, March 12 it's Movie Day with a trip to the Oshawa Centre for a scavenger hunt and a movie at Famous Players. Cost is $10 and it's for kids six years and older. Tuesday is Splash and Magic Day with swim- ming, crafts, games and an opportunity to learn magic at the Grandview Children's Centre in Oshawa. Cost is $10 and kids must be five years and older to register. A trip to the Science Centre in Toronto is planned for Wednesday. Cost is $15 and children must be at least seven- years-old. On Thursday, it's a therapist will join in the . activities. The cost for Bowling Bonanza. North End Bowl in Oshawa is the site for a bowling party for Grandview kids. Cost is $10 for kids five years and up. March Break activities wrap up on Friday, March 16 with a St. Patrick's Day Party at Grandview. There will be crafts and games plus a scavenger hunt for the pot of gold. A registered music fun. Cost is $10 and kids must be five years and older to register. Pre-registration is required for . all the all five days is $50. To register for any of the March Break programs, or for more information, please call Grandview Recreation Department at (905) 728-1673, ext. 265.